Viral Load as Predictor of Crimean-Congo Hemorrhagic Fever Outcome
نویسندگان
چکیده
We used quantitative real-time reverse transcription-PCR to measure viral load in serum from 24 patients in Kosovo who had acute Crimean-Congo hemorrhagic fever. Viral load correlated with clinical disease and antibodies and could be used as a predictor of disease outcome.
منابع مشابه
THE EFFICACY OF ORAL RIBAVIRIN IN THE TREATMENT OF 81 PROVED CASES OF CRIMEAN-CONGO HEMORRHAGIC FEVER (CCHF) IN IRAN (1999-2001)
Crimean-Congo Hemorrhagic Fever is a fatal viral disease that occurs in some parts of Africa, Asia, Eastern Europe and the Middle-East. Primarily it is a zoonosis but can be seen sporadically in humans. Recently outbreaks have been reported from Pakistan, Afghanistan, Saudi Arabia, United Arab Emirates and Iran. In this retrospective study, we evaluated the efficacy of oral Ribavirin in the...
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Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal disease affecting multiple organ systems. To determine the association between viral load and severity of CCHF infection, quantitative measurement of CCHF virus was performed using 1-step reverse-transcriptase polymerase chain reaction for 36 patients with CCHF infection. Viral loads ranged from 1.1x10(3) copies/mL to > or = 9.9x10(9...
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